structure-activityrelationships相关论文
Evaluation of antimicrobial and anticancer activities of three peptides identified from the skin sec
The skins of frogs of the family Ranidae are particularly rich sources of biologically active pep-tides,among which anti......
Recent studies have established that histone deacetylase 6(HDAC6)is associated with oncology,immune-inflammatory and neu......
Combined Topomer CoMFA and Hologram QSAR studies of a series of pyrrole derivatives as Potential HIV
In order to understand the relationship between the structure and activity of HIV fusion inhibitors,Topomer Comparative ......
Discovery of Novel Diarylpyrimidines as Potent HIV NNRTIs via A Structure-guided Core-refining Appro
Guided by crystal structures of HIV-1 RT/DAPY complex and molecular modeling studies,a series of novel DAPY derivatives ......
...
...
Discovery of Selective Phosphodiesterase- 4 Inhibitors with Anti-neuroinflammation Potential Exhibit
Depression involving neuroinflammation is one of the most common disabling and life-threatening psychiatric disorders....
Me2AlSEt-Promoted Domino Dieckmann Cyclization Enables the Total Synthesis of Polycyclic Polyprenyla
A bioinspired,Me2AlSEt-promoted domino Dieckmann cyclization was developed for the syntheses of nine polycyclic polypren......
Design,Synthesis,and Evaluation of Fungicidal Activity of Novel Pyrazole-Containing Strobilurin Deri
Main observation and conclusionrnIn searching for novel fungicidal leads,a series of pyrazole-containing strobilurins we......
Synthesis and Structure-Activity Relationships of Ring-Opened Bengamide Analogues against Methicilli
Methicillin-resistant Staphylococcus aureus (MRSA) has become a major threat on public health because of the increase of......
